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The manganese nitrosyl complex derived from a designed pentadentate ligand with one carboxamido group N,N-bis(2-pyridylmethyl)amine-N-ethyl-2-pyridine-2-carboxamide (PaPy3H; H is the dissociable carboxamide H), namely, [Mn(PaPy3)(NO)]ClO4 (1), serves as an excellent biocompatible… Click to show full abstract
The manganese nitrosyl complex derived from a designed pentadentate ligand with one carboxamido group N,N-bis(2-pyridylmethyl)amine-N-ethyl-2-pyridine-2-carboxamide (PaPy3H; H is the dissociable carboxamide H), namely, [Mn(PaPy3)(NO)]ClO4 (1), serves as an excellent biocompatible source of nitric oxide (NO) when exposed to low power (10-100 mW/cm2) visible light. This complex has afforded a series of NO delivery platforms that could find applications in combating chronic infections by drug-resistant bacteria under the control of light.
Journal Title: Journal of inorganic biochemistry
Year Published: 2022
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