LAUSR

Background Since the COVID-19 outbreak, four cities -- Wuhan, Beijing, Urumqi and Dalian -- have experienced the process from outbreak to stabilization. Geographic location, population density, population mobility and epidemic prevention measures show relatively large differences among the four regions of interest, providing the possibility to use these regional conventional attributes and pathological infectious disease attributes to assess the risk of an infectious disease outbreak in an area. Methods According to the China Statistical Yearbook and China Center for Disease Control records, regional, pathological, medical and response attributes were selected as regional vulnerability factors of infectious diseases. Then the Analytic Hierarchy Process (AHP) method was used to build a regional vulnerability index model for the infectious disease. Results The influence of the COVID-19 outbreak at a certain place was assessed computationally in terms of the number of days of epidemic duration and cumulative number of infections, and then fitted to the city data. The resulting correlation coefficient was 0.999952. The range of the regional vulnerability index for COVID-19 virus was from 0.0513 to 0.9379. The vulnerability indexes of Wuhan, Urumqi, Beijing and Dalian were 0.8733, 0.1951, 0.1566 and 0.1119, respectively. Conclusions The lack of understanding of the virus became the biggest breakthrough point for the rapid spread of the virus in Wuhan. Due to inadequate prevention and control measures, the city of Urumqi was unable to trace the source of infection and close contacts, resulting in a relatively large impact. Beijing has both high population density and migration rate, which imply that the disease outbreak in this city had a great impact. Dalian has perfect prevention and good regional attributes. In addition, the regional vulnerability index model was used to analyze other Chinese cities. Accordingly, the regional vulnerability index and the prevention and control suggestions for them were discussed.