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Sweet-MXene hydrogel with mixed-dimensional components for biomedical applications.

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Biodegradable hydrogels are promising extracellular matrix-like materials for biomedical applications due to their high compatibility, ease of administration and minimal invasion. The injectable hydrogels to be considered for regenerative therapies… Click to show full abstract

Biodegradable hydrogels are promising extracellular matrix-like materials for biomedical applications due to their high compatibility, ease of administration and minimal invasion. The injectable hydrogels to be considered for regenerative therapies should mimic the intrinsic properties of tissues, i.e. self-healing and swelling. Here, we present facile electrically conductive sweet-MXene (S-MXene) hydrogel with novel mixed-dimensional compositions including natural zero dimensional (0D) fluorescent carbon dots in honey, delaminated 2D fluorescent titanium carbide (Ti3C2) nanosheets and bioinspired 3D crosslinked polymeric chitosan networks. The developed versatile (Ti3C2-MXene-honey-chitosan) heterostructure exhibited excellent porous architecture with desired swelling and controlled degradation. This electrically conductive composite is highly biocompatible, it supported cell attachment and survival.

Keywords: mixed dimensional; sweet mxene; hydrogel mixed; mxene hydrogel; biomedical applications

Journal Title: Journal of the mechanical behavior of biomedical materials
Year Published: 2019

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