LAUSR

OBJECTIVE This study aims at assessing the global dynamic behavior, closing energy and turbulence characteristics of self-expandable textile (inclined and straight yarn) transcatheter aortic valves (TAV) versus bioprosthetic TAVs. METHODS Two self-expandable textile TAVs one with inclined yarn textile and another with straight yarn textile leaflets were assessed in a pulse duplicator and compared with a self-expandable commercial bioprosthetic TAV under physiological pressure and flow. Particle Image Velocimetry and high-speed imaging were performed. Effective orifice areas (EOA), leakage fractions (LF), Pinwheeling indices (PI), closing energy (E), viscous shear stresses (VSS) and Reynolds shear stresses (RSS) were calculated. RESULTS (a) EOAs and LFs were 2.27 ± 0.03 cm2, 31.7 ± 0.6%; 2.25 ± 0.08 cm2, 26.6 ± 0.7%; and 1.63 ± 0.01 cm2, 29.1 ± 1.25% for inclined textile, bioprosthetic and straight textile TAV respectively (p < 0.0001). (b) Following same order, PIs were significantly different going from 1.16 ± 0.21%, 8.48 ± 0.8% and 8.865 ± 0.58% with the exception of CoreValve and straight yarn valve (p = 0.37); (c) E is lowest for straight textile TAV (0.0024 ± 0.0017 J), followed by bioprosthetic valve (0.00259 ± 0.0011 J) and then 45° Oriented Yarn Valve (0.00334 ± 0.03 J) (d) At peak systole, the highest RSS distribution was with the Straight textile TAV reaching up to 330Pa. The bioprosthetic TAV shows the smallest range with RSS reaching around 230Pa and the inclined textile TAV up to 280Pa. VSS limits were comparable among the 3 valves ranging between 5.2Pa and 5.7Pa. CONCLUSION Hemodynamic similarities were found between the textile self-expandable valves and the bioprosthetic valve. This study constitutes another step towards showing the potential that textile valves have to become an alternative for the biological ones.