LAUSR

This study aims to evaluate the effects of implant macrogeometry on the early period of the osseointegration process, comparing four different implant models through biomechanical and histological analysis after implantation in rabbit tibiae. Twenty New Zealand rabbits were used, evaluated at two different times (21 and 28 days) after installation of the implant. Eighty implants with different macrogeometries were used, forming four groups (n = 20 per group): cylindrical implants Ø4.1 mm and 8 mm in length (STRc group); cylindrical-conical implants Ø4.1 mm and 8 mm in length (STRt group); tapered implants Ø4.3 mm and 8 mm in length (NOBt group); and tapered implants with healing chambers Ø4.0 mm and 8 mm in length (MAEt group). Ten samples from each group were analyzed at each proposed time. The initial implant stability quotient (ISQ) was measured by resonance frequency analysis, both at the time of installation and at the time of sacrifice. In the histological sections, the percentage of bone-implant contact (BIC%), newly formed bone, osteoid matrix, and medullary spaces were measured in the pre-determined cortical and medullary bone portion for each sample. The three tapered implant groups (STRt, NOBt, and MAEt) showed higher values for the analyzed parameters in the early osseointegration period, in comparison with the cylindrical implant group (STRc). In all parameters, the three tapered groups showed no difference (p > 0.05); however, all three tapered groups presented significant differences, when compared to the cylindrical group (p < 0.05). No correlation was detected between the parameters analyzed. Within the limitations of the present study, in all parameters analyzed, the tapered implants demonstrated greater results when compared to the cylindrical implants.