LAUSR

Study Objective The aim of this study was to assess the surgical and oncologic outcome of laparoscopic primary cytoreductive surgery on advanced epithelial ovarian cancer in comparison with conventional laparotomy surgery. Design Retrospective cohort study. Setting University hospital in Korea. Patients or Participants Patients with FIGO stage up to III ovarian cancer undergoing laparoscopic primary cytoreductive surgery from January 2011 to March 2019 were matched to controls treated with laparotomic cytoreduction during the same period. Interventions Laparoscopic and laparotomic optimal cytoreduction. Measurements and Main Results The surgical and long-term outcome with advanced ovarian cancer were compared. The laparoscopic group (n=30) and laparotomic group (n=24) had similar age, BMI, stages, histologic type and final stage. There were no significant differences in operating time (P = 0.08) and blood loss (P = 0.34). The laparoscopic group exhibited significantly shorter hospital stay (P = 0.002) and time to start to treat adjuvant chemotherapy (P Conclusion Laparoscopic and laparotomic primary cytoreduction were similar in surgical and oncologic outcome. Laparoscopic primary cytoreduction in highly selected patients with advanced ovarian cancer was feasible and not to inferior in laparotomic surgery. Prospective randomized trials are required to evaluate the overall oncologic outcomes.