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Absence of SARS-CoV-2 RNA in peritoneal fluid during surgery in COVID-19 positive pregnant women

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Study Objective: COVID-19 infection poses significant risks during surgical interventions. We investigated the intraperitoneal presence of SARS-CoV-2 in COVID-19 positive patients. Design: A prospective group study. Setting: Department of Obstetrics… Click to show full abstract

Study Objective: COVID-19 infection poses significant risks during surgical interventions. We investigated the intraperitoneal presence of SARS-CoV-2 in COVID-19 positive patients. Design: A prospective group study. Setting: Department of Obstetrics and Gynecology designated for COVID-19 patients, Central Clinical Hospital of the Ministry of Interior, Warsaw Patients: Overall, 65 pregnant women with COVID-19 infection underwent caesarian section. The diagnosis was confirmed either by positive antigen test or by positive RT-PCR assay performed within no more than 13 days prior to the operation. Interventions: On the day of the operation, a nasopharyngeal swab was taken, and peritoneal fluid was collected at the beginning of the operation. Both the nasopharyngeal swab and peritoneal fluid samples were tested for SARS-CoV-2. Measurements and Main Results: A total of 65 pregnant women with COVID-19 infection were enrolled in the study. The SARS-CoV-2 RNA test by nasopharyngeal swab produced positive results in 34 patients. In this group as well as in 31 non-confirmed patients all peritoneal fluid samples tested negative for SARS-CoV-2 RNA. Conclusion: These results suggest a low risk of COVID-19 transmission from the peritoneal cavity at the time of laparoscopy or laparotomy

Keywords: cov rna; pregnant women; peritoneal fluid; covid; sars cov

Journal Title: Journal of minimally invasive gynecology
Year Published: 2021

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