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Evaluation of time to antibiotic administration for suspected late-onset sepsis in the Neonatal Intensive Care Unit: A quality improvement project

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Abstract Late-onset sepsis is a significant cause of morbidity and mortality, with mortality increasing by 8–9% for each hour delay in antibiotics. The primary objective of this study is to… Click to show full abstract

Abstract Late-onset sepsis is a significant cause of morbidity and mortality, with mortality increasing by 8–9% for each hour delay in antibiotics. The primary objective of this study is to evaluate the time to antibiotic administration for late-onset sepsis after implementation of a newly developed process for performing sepsis evaluations. A retrospective chart review was conducted utilizing electronic medical records to obtain data for select time points within the sepsis evaluation process. There were 42 patients evaluated prior to the quality improvement project (Group 1) and 59 patients evaluated after (Group 2). The average time to antibiotic administration was 2 h and 48 min in Group 1 and 1 h and 7 min in Group 2 (p

Keywords: time; sepsis; late onset; onset sepsis; time antibiotic; antibiotic administration

Journal Title: Journal of Neonatal Nursing
Year Published: 2021

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