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periependymal or diencephalic region, the areas considered as hallmarks of anti-AQP4 antibody positive-NMOSD brain lesions. Only one out of the four cases had prior infection, and the patients tended to… Click to show full abstract
periependymal or diencephalic region, the areas considered as hallmarks of anti-AQP4 antibody positive-NMOSD brain lesions. Only one out of the four cases had prior infection, and the patients tended to relapse without induction of maintenance therapy. Conclusion: Our findings indicate that anti-MOG antibody positive brain lesions are highly inflammatory in character, often presenting with meningitis. It is encephalitis with pathophysiology different from anti-AQP4 antibody mediated-astrocytic dysfunction found in seropositive NMO and yet clinically distinct from monophasic ADEM.
Journal Title: Journal of the Neurological Sciences
Year Published: 2017
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