LAUSR

Introduction: The purpose of this study was to evaluate dentinal tubule penetration (DTP) of calcium hydroxide (CH) and triple antibiotic paste (TAP) when performed with distilled water (DW) or a low surface tension liquid (ie, propylene glycol [PG]). Methods: Root apices of 40 single‐rooted premolars were removed to obtain 14‐mm roots in length. Root canals were enlarged to simulate immature teeth. After smear layer removal, the roots were randomly divided into 4 groups (n = 10) according to the root canal medicaments and the vehicles used: group 1:TAP + DW, group 2: TAP + PG, group 3: CH + DW, and group 4:CH + PG. Root canal medicaments were labeled with 0.1% rhodamine and applied into the canals using a Lentulo spiral. Specimens were molded into acrylic blocks, and 1‐mm‐thick sections were obtained from the middle third of each root. Specimens were mounted onto glass slides and scanned under a confocal laser scanning microscope. DTP depth, percentage, and area were measured using imaging software. Kruskal‐Wallis and Mann‐Whitney U tests were used for statistical analysis. The level of significance was set at P < .05. Results: No significant difference was found among the experimental groups in terms of both percentage and depth of DTP (P > .05). CH had a lower penetration area compared with TAP regardless of the vehicle used (P < .05). Conclusions: A low surface tension vehicle did not alter the penetration of CH and TAP. HighlightsCalcium hydroxide and triple antibiotic paste have a similar dentinal tubule penetration ability.Calcium hydroxide and triple antibiotic paste can reach up to 2.75 and 2.63 mm, respectively.The vehicle with a low surface tension did not raise the ability of penetration of the medicaments.