LAUSR

Introduction: The aim of this study was to perform a critical review of the literature that investigated the association between diabetes and apical periodontitis. Methods: An electronic search was performed on PubMed/MEDLINE, LILACS, Scientific Electronic Library Online (Scielo), and Cochrane Collaboration databases. Human studies assessing the effect of diabetes in apical periodontitis development or in healing after root canal treatment were included. The outcome was apical periodontitis. Results and Conclusions: Nine articles were included. The results presented in the literature to date are still scarce and incipient, and the evidence for such an association is not yet conclusive. However, the published results trend to converge on a positive association between diabetes and a larger number of periapical lesions. HighlightsA critical review of the literature that has investigated the association between diabetes and apical periodontitis of endodontic origin was performed.The majority of the studies indicate an association between apical periodontitis and diabetes.The relationship between diabetes and apical periodontitis remains unproven.Dentists should be alert to the systemic conditions of the patients to plan an appropriate treatment and warn the patient about potentially unfavorable prognostic.