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BACKGROUND The presence of anaplastic and sarcomatoid components in ovarian mucinous carcinoma is extremely rare. CASE A 64-year-old woman underwent radical surgery for right ovarian cancer. Pathological examination showed mucinous… Click to show full abstract
BACKGROUND The presence of anaplastic and sarcomatoid components in ovarian mucinous carcinoma is extremely rare. CASE A 64-year-old woman underwent radical surgery for right ovarian cancer. Pathological examination showed mucinous adenocarcinoma with a focal mural nodule of anaplastic and sarcomatoid carcinoma (FIGO stage IIB). She underwent adjuvant chemotherapy but developed severe respiratory failure and died after 9 months. Autopsy showed that the bilateral pulmonary parenchyma was filled with a multinodular hemorrhagic mass, and the cardiac wall had a massive invasive lesion. Histopathological examination of the lung and myocardium revealed diffuse invasion of the anaplastic carcinoma component with infiltrating osteoclastic giant cells. CONCLUSION This case is very rare, and the clinical management of anaplastic carcinoma arising in mucinous neoplasms remains challenging.
Journal Title: Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
Year Published: 2019
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