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Pain is a common symptom in pediatric patients with cancer, and the majority of these patients in palliative care will receive opioids. Traditional opioids have several drawbacks, including their adverse… Click to show full abstract
Pain is a common symptom in pediatric patients with cancer, and the majority of these patients in palliative care will receive opioids. Traditional opioids have several drawbacks, including their adverse effects, inconsistent or diminishing efficacy, and limited available routes of administration. Buprenorphine is an attractive option for pain management due to its safety profile, unique pharmacology, and availability in transdermal, buccal, parenteral, and sublingual dosage forms. Unfortunately, data supporting the use of buprenorphine in pediatric pain patients, particularly sublingual buprenorphine, is lacking. This case report describes the feasibility of sublingual buprenorphine use in pediatric patients with complex cancer-related pain.
Journal Title: Journal of pain and symptom management
Year Published: 2020
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