LAUSR

HighlightsOptoelectronic flow‐through detectors for iron determination have been developed.Flow analysis systems for iron determination have been developed.Developed detectors and systems are useful for analysis of supplements.Developed systems can be used as monitors of iron release from pharmaceuticals. Abstract Compact flow‐through optoelectronic detectors fabricated by pairing of light emitting diodes have been applied for development of economic flow analysis systems dedicated for iron ions determination. Three analytical methods with different chromogens selectively recognizing iron ions have been compared. Ferrozine and ferene S based methods offer higher sensitivity and slightly lower detection limits than method with 1,10‐phenantroline, but narrower ranges of linear response. Each system allows detection of iron in micromolar range of concentration with comparable sample throughput (20 injections per hour). The developed flow analysis systems have been successfully applied for determination of iron in diet supplements. The utility of developed analytical systems for iron release studies from drug formulations has also been demonstrated.