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Antibacterial activity of N-halamine decorated mesoporous silica nanoparticles

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N-halamine decorated mesoporous silica nanoparticles (mSiO2/halamine NPs) were prepared by coating mSiO2 NPs with poly (1-allylhydantoin-co-methyl methacrylate) (AH-co-MMA) by the aid of the radical polymerization, followed by chlorination treatment. The… Click to show full abstract

N-halamine decorated mesoporous silica nanoparticles (mSiO2/halamine NPs) were prepared by coating mSiO2 NPs with poly (1-allylhydantoin-co-methyl methacrylate) (AH-co-MMA) by the aid of the radical polymerization, followed by chlorination treatment. The sterilizing effect on the bacterial strain is investigated by incubating Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). Results indicated that the mSiO2/halamine NPs had excellent antibacterial activity and no significant change occurred in antibacterial efficiency after five recycle experiments.

Keywords: halamine decorated; decorated mesoporous; mesoporous silica; silica nanoparticles; antibacterial activity; halamine

Journal Title: Journal of Physics and Chemistry of Solids
Year Published: 2017

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