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Highlights • A model of engineered underdominance (UD) gene drive is proposed.• Numerical results suggest that UD could be an effective tool for disease control.• Success/failure of UD is affected… Click to show full abstract
Highlights • A model of engineered underdominance (UD) gene drive is proposed.• Numerical results suggest that UD could be an effective tool for disease control.• Success/failure of UD is affected by release strategy and fitness of mosquitoes.• A single release of only males with weakly suppressed lethals cannot succeed.
Keywords:
underdominance gene;
conditions success;
engineered underdominance;
gene drive
Journal Title: Journal of Theoretical Biology
Year Published: 2017
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Journal Title: Journal of Theoretical Biology
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!