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Conclusion: We interrogated the characteristics of ERBB2 exon 20 insertions in a large cohort from single ethnicity. It demonstrated the response heterogeneity to afatinib among different ERBB2 exon 20 insertion… Click to show full abstract
Conclusion: We interrogated the characteristics of ERBB2 exon 20 insertions in a large cohort from single ethnicity. It demonstrated the response heterogeneity to afatinib among different ERBB2 exon 20 insertion subtypes. It highlighted the importance to correlate drug efficacy with specific ERBB2 exon 20 insertion variants in clinical application.
Keywords:
reported outcomes;
checkmate 078;
outcomes pros;
078 patient;
erbb2 exon;
patient reported
Journal Title: Journal of Thoracic Oncology
Year Published: 2018
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Journal Title: Journal of Thoracic Oncology
Year Published: 2018
Link to full text (if available)
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recommendations!