LAUSR

between oral leukoplakia and lung cancer in the Linxian General Population Trial cohort. Method: The Linxian General Population Trial cohort, with 29,584 healthy adults enrolled in 1985 and followed through the end of 2012. With collected baseline data, hazard ratios (HR) and 95% confidence intervals (95% CI) for developing lung cancer were estimated using Cox proportional hazard models. Results: Overall, a total of 29449 were included in the final analysis. During 28 years of follow up, we confirmed a total of 277 incident lung cancer cases. Overall, participants with oral leukoplakia had little risk for developing lung cancer (HR1⁄41.01, 95%CI: 0.67, 1.16). No significant associations were observed for lung cancer in either all subjects or subgroups. Conclusion: Our results suggest that oral leukoplakia is not associated with increased risk of lung cancer mortality. Future studies are needed to confirm these findings. Keyword: oral leukoplakia; lung cancer; Linxian General Population Trial