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Silymarin improved the growth performance via modulating the microbiota and mucosal immunity in Escherichia coli-challenged broiler chicks

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Abstract The present study was carried out to investigate the effects of dietary supplemental silymarin on growth performance, intestinal microbiota, and jejunal health indices in broiler chicks challenged with Escherichia… Click to show full abstract

Abstract The present study was carried out to investigate the effects of dietary supplemental silymarin on growth performance, intestinal microbiota, and jejunal health indices in broiler chicks challenged with Escherichia coli (E. coli) O78:K80. For this purpose, 384 seven-day-old Ross broiler chicks were randomly allocated to eight experimental treatments with four replicates of 12 birds each. The treatments consisted of two microbial conditions (unchallenged and challenged with E. coli O78:K80) with further division into four additive supplementations (no additive, additions of 500 and 1000 ppm of silymarin, and antibiotic addition as the positive control). The birds were orally infected with E. coli O78:K80 at 1 × 109 cfu from 7 to 28 d of age. Results showed that E. coli infection led to the declines (P

Keywords: broiler chicks; broiler; escherichia coli; growth performance

Journal Title: Livestock Science
Year Published: 2021

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