LAUSR

Introduction Profound primary hypothyroidism in children causes generally delayed pubertal development. Rare association with precocious puberty may occur especially in long standing untreated patients. The cardinal features of hypothyroidism inducing isosexual precocious puberty include thelarche, galactorrhea and/or menarche. Other characteristics features are the absence of sexual hair and retardation of linear growth [1,2]. This condition was described in 1960 by Van Wyk–Grumbach in a report of three cases of long standing hypothyroidism, presented with menarche, premature thelarche and galactorrhea [3]. We report an 8 year-old-girl who presented with vaginal bleeding and short stature. Subsequent investigations led to a diagnosis of autoimmune hypothyroidism.