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Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia

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Chronic Myelomonocytic Leukemia (CMML) is a blood malignancy that presents with splenomegaly in up to 40% of the patients; however, a pathological splenic rupture is very rare. We describe a… Click to show full abstract

Chronic Myelomonocytic Leukemia (CMML) is a blood malignancy that presents with splenomegaly in up to 40% of the patients; however, a pathological splenic rupture is very rare. We describe a 50-year-old male, who presented to hematology clinic twice during 5-year period, asymptomatic with thrombocytopenia and monocytosis but was noncompliant to any diagnostic workup. He finally presented to us with hypovolemic shock secondary to pathological splenic rupture and subsequent blood loss. Patient underwent emergency laparoscopic splenectomy and stabilized. During the stay at hospital, his complete workup revealed the diagnosis of Chronic Myelomonocytic Leukemia. Although splenomegaly is common in CMML, it rarely result in its rupture and so this complication is often overlooked. This case is reviewed in the light of handful cases described in medical literature previously.

Keywords: rupture; complication; splenic rupture; chronic myelomonocytic; myelomonocytic leukemia

Journal Title: Leukemia Research Reports
Year Published: 2020

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