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Abstract Foodborne pathogen is a major threat to human health. In this study, we evaluated the bactericidal efficacy of curcumin-based photodynamic inactivation (PDI) against Listeria monocytogenes, elucidated its underlying bactericidal… Click to show full abstract
Abstract Foodborne pathogen is a major threat to human health. In this study, we evaluated the bactericidal efficacy of curcumin-based photodynamic inactivation (PDI) against Listeria monocytogenes, elucidated its underlying bactericidal mechanisms including membrane damage, oxidative stress and protein degradation. Depending on curcumin concentration and illumination duration, the reactive oxygen species (ROS) increased rapidly after PDI treatment, resulting in severe cell membrane damage and protein degradation. Meanwhile, the activity of ROS defense enzymes such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) was inhibited significantly (p
Journal Title: Lwt - Food Science and Technology
Year Published: 2021
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