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Highlights • Transcriptomic changes are more similar within mutant mice that show either lengthened or shortened lifespan.• The major transcriptomic differences between long- and short-lived mice are in genes controlling… Click to show full abstract
Highlights • Transcriptomic changes are more similar within mutant mice that show either lengthened or shortened lifespan.• The major transcriptomic differences between long- and short-lived mice are in genes controlling mitochondrial metabolism.• Gene expression changes in short-lived, progeroid, mutant mice resemble those seen during normal ageing.
Keywords:
mutant mice;
normal ageing;
long short;
mitochondrial metabolism;
mice;
short lived
Journal Title: Mechanisms of Ageing and Development
Year Published: 2021
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Journal Title: Mechanisms of Ageing and Development
Year Published: 2021
Link to full text (if available)
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recommendations!