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Electrospun Xanthan gum-Chitosan nanofibers as delivery carrier of hydrophobic bioactives

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Abstract Viscoelastic gels of xanthan gum-chitosan(X-Ch) in formic acid were electrospun to produce nanofibers, stable in aqueous media, for the encapsulation and release of curcumin (Cu). After 120 h, the nanofibers… Click to show full abstract

Abstract Viscoelastic gels of xanthan gum-chitosan(X-Ch) in formic acid were electrospun to produce nanofibers, stable in aqueous media, for the encapsulation and release of curcumin (Cu). After 120 h, the nanofibers released lower amount of curcumin (∼20%) at pH 2.2 comparatively to the release in neutral media (∼50%), suggesting that X-Ch nanofibers could be used as a carrier for the encapsulation of hydrophobic bioactive compounds with long-term pH-stimulated release properties.

Keywords: nanofibers delivery; gum chitosan; xanthan gum; carrier; chitosan nanofibers; electrospun xanthan

Journal Title: Materials Letters
Year Published: 2018

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