Abstract Composite scaffolds were successfully obtained using sol-gel derived 58S bioactive glass particles and poly(e-caprolactone) pellets. Camphene was used as the freezing vehicle. No sintering step was used, which represents… Click to show full abstract
Abstract Composite scaffolds were successfully obtained using sol-gel derived 58S bioactive glass particles and poly(e-caprolactone) pellets. Camphene was used as the freezing vehicle. No sintering step was used, which represents a great advantage in terms of energy and time-saving. The prepared scaffolds showed a mechanical behavior similar to elastomeric cellular solids and Young’s modulus of 46.7 ± 9.4 MPa, which may allow their use in load-bearing applications. Cytotoxicity tests revealed that the composites promoted the growth of human osteosarcoma cells. The formation of a hydroxyapatite layer on the surface of the samples was also observed after soaking them in a simulated body fluid solution.
               
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