LAUSR

Abstract Here, the nanoparticles (NPs) of CdO/SnO2 were prepared by co-precipitation method in alkaline phase at low temperature. The characterization of CdO/SnO2 NPs were analyzed by X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscope (FESEM), X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDS) analysis. To fabricate the sensor, glassy carbon electrode (GCE) was coated by CdO/SnO2 NPs with 5% nafion suspension. The resulted sensor was applied to detect L-tyrosine (L-tyr) in buffer phase. A linear relation current versus concentration known as calibration curve was made. The sensor sensitivity (11.848 µAµm-1cm-2) is calculated from the slope of calibration curve. Recognizing the maximum linear region in calibration curve (regression coefficient R2=0.99), the linear dynamic range (0.1nM∼0.01mM) is used. Finally, the lower limit of detection (97.93±4.89 pM) is estimated by applying the signal to noise ratio of 3 from the calibration curve. During the sensing performances, it was found as reliable, reproducible and long-term stable sensor and validated to detect the real biological samples by electrochemical approach in room conditions.