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Abstract Background and objective Myelofibrosis is an infrequent chronic myeloproliferative neoplasm. We aimed to describe the clinico-biological characteristics, treatment, and evolutive course of myelofibrosis patients in Spain. Material and methods… Click to show full abstract
Abstract Background and objective Myelofibrosis is an infrequent chronic myeloproliferative neoplasm. We aimed to describe the clinico-biological characteristics, treatment, and evolutive course of myelofibrosis patients in Spain. Material and methods A total of 1000 patients from the Spanish Registry of Myelofibrosis diagnosed with primary (n = 641) or secondary (n = 359) myelofibrosis were analysed. Results Median age was 68 years. The frequency of constitutional symptoms, moderate to severe anaemia (Hb Conclusion Myelofibrosis is a disabling condition mainly affecting elderly people. Its treatment is mostly driven by symptom control. Despite its clinical heterogeneity, several prognostic models are useful to select candidates for transplantation.
Journal Title: Medicina Clinica
Year Published: 2020
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