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Prevention of catheter-related urinary tract infections: The octenidine hypothesis.

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Urinary bladder dysfunction and voiding disorders lead to the accumulation of residual urine. Left untreated, these conditions result in urinary tract infections. In order to empty the urinary bladder properly,… Click to show full abstract

Urinary bladder dysfunction and voiding disorders lead to the accumulation of residual urine. Left untreated, these conditions result in urinary tract infections. In order to empty the urinary bladder properly, clean intermittent catheterization procedures are highly advocated as an effective measure. Clean intermittent catheterization is a repetitive procedure, which includes inserting the urinary catheter into the urinary bladder. However, inserting the urinary catheter several times a day into the urinary bladder further compromises patient's safety since the procedure itself is a risk for acquiring catheter-related urinary tract infections. In order to prevent catheter contamination and further infections, new catheter models or catheterization techniques need to be developed. In this paper, a possible method for protection of catheter surface is hypothesized. Using octenidine as an effective antiseptic agent for creating an antimicrobial layer might prove effective against bacterial adhesion and consequent catheter contamination. Additionally, using octenidine as catheter coating further facilitates the catheterization procedure. An uncontaminated catheter throughout the whole catheterization process is the main goal of the procedure. Achieving it would prove beneficial to both patients and the healthcare system due to the absence of infections, increase in patients' quality of life and an overall cost reduction.

Keywords: urinary tract; catheter; catheter related; tract infections; urinary bladder

Journal Title: Medical hypotheses
Year Published: 2020

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