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Abstract One major part of therapeutic oncolytic viruses (OV) manufacturing is a membrane-based process with a major challenge of membrane fouling and consequent product loss. A small-scale microfiltration setup was… Click to show full abstract
Abstract One major part of therapeutic oncolytic viruses (OV) manufacturing is a membrane-based process with a major challenge of membrane fouling and consequent product loss. A small-scale microfiltration setup was developed, allowing online transmembrane pressure (TMP) measurement through a constant flux filtration using a low volume of a representative OV solution (
Keywords:
additives filterability;
process;
oncolytic viruses;
probing effects;
effects additives;
microfiltration
Journal Title: Journal of Membrane Science
Year Published: 2020
Link to full text (if available)
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Journal Title: Journal of Membrane Science
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!