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Liver-targeted delivery of nucleic acid by liposomes modified with a glycoconjugate

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A drug delivery system based on liposomes has been modified by targeted vectors based on a glycoconjugate, and the vector structure has been optimized. The glycoconjugate in liposomes almost fourfold… Click to show full abstract

A drug delivery system based on liposomes has been modified by targeted vectors based on a glycoconjugate, and the vector structure has been optimized. The glycoconjugate in liposomes almost fourfold increases the transfection efficiency of the delivery system in specific human liver cell line (HepG2) in comparison with that of unmodified lipopeptide-based liposomes.

Keywords: liver targeted; delivery; liposomes modified; targeted delivery; nucleic acid; delivery nucleic

Journal Title: Mendeleev Communications
Year Published: 2017

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