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A facile, diastereoselective method for the synthesis of diaziridines with C- and N-cyclopropyl substituents has been developed, N-cyclopropyldiaziridines being for the first time synthesized. The method is based on one-pot… Click to show full abstract
A facile, diastereoselective method for the synthesis of diaziridines with C- and N-cyclopropyl substituents has been developed, N-cyclopropyldiaziridines being for the first time synthesized. The method is based on one-pot three-component condensation of cyclopropyl-containing carbonyl compounds, primary aliphatic amines including cyclopropylamine, and N-chloroalkylamines in organic solvents in the presence of bases under mild conditions.
Keywords:
structures comprising;
diaziridine cyclopropane;
hybrid structures;
synthesis hybrid;
comprising diaziridine;
cyclopropane rings
Journal Title: Mendeleev Communications
Year Published: 2018
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Journal Title: Mendeleev Communications
Year Published: 2018
Link to full text (if available)
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recommendations!