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New 2-amino-4-aryl-3-cyanopyridines were obtained by the three-component condensation of arylidenemalononitriles, malononitrile and (di)amine system or acetoacetanilide. Antibacterial activity of all synthesized compounds against the Gram-negative bacteria E. coli and the… Click to show full abstract
New 2-amino-4-aryl-3-cyanopyridines were obtained by the three-component condensation of arylidenemalononitriles, malononitrile and (di)amine system or acetoacetanilide. Antibacterial activity of all synthesized compounds against the Gram-negative bacteria E. coli and the Gram-positive B. subtilis was tested, the only representative showed a substantial antimicrobial effect.
Keywords:
amino;
activity amino;
antibacterial activity;
amino cyanopyridine;
cyanopyridine derivatives
Journal Title: Mendeleev Communications
Year Published: 2020
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Journal Title: Mendeleev Communications
Year Published: 2020
Link to full text (if available)
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recommendations!