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Graphical abstract Segmentation of the Lateral Ventricular Perimeter (LVP), on an axial mean diffusivity map of an infant with postheorrhgaic hydrocephalus (PHH). A MATLAB-based script segments a homogenous LVP layer… Click to show full abstract
Graphical abstract Segmentation of the Lateral Ventricular Perimeter (LVP), on an axial mean diffusivity map of an infant with postheorrhgaic hydrocephalus (PHH). A MATLAB-based script segments a homogenous LVP layer using high spatial resolution parameters (voxel size 1.2 × 1.2 × 1.2 mm3) to perform diffusion MRI analysis of the innermost layer of the LVP. The LVP, which comprises the ventricular zone (VZ), subventricular zone and the subjacent periventricular white matter (PVWM) is critical for forming a brain-CSF barrier and global cortical development (. In PHH, and other neurological conditions the LVP is disrupted and has been associated with severe neuromotor and cognitive impairment. Modified from Rodriguez et. al. 2012. Biol Res 45: 231-241Image, graphical abstract
Journal Title: MethodsX
Year Published: 2020
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