Photo from wikipedia
Brucella infection activates the immune system and favors the differentiation of CD4+ and CD8+ T cells. To persist during a long time inside macrophages evading immune surveillance of these T… Click to show full abstract
Brucella infection activates the immune system and favors the differentiation of CD4+ and CD8+ T cells. To persist during a long time inside macrophages evading immune surveillance of these T cells the pathogen must exploit different evasion strategies. We review the mechanisms whereby Brucella, through TLR signaling, inhibits MHC class I and II antigen presentation, allowing infected macrophages to become effective niches for Brucella survival.
Keywords:
presentation brucella;
antigen presentation;
brucella many;
antigen;
inhibition antigen
Journal Title: Microbes and infection
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Microbes and infection
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!