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BACKGROUND To reduce the incidence of osteomyelitis infection, local antibiotic impregnated delivery systems are commonly used as a promising and effective approach to deliver high antibiotic concentrations at the infection… Click to show full abstract
BACKGROUND To reduce the incidence of osteomyelitis infection, local antibiotic impregnated delivery systems are commonly used as a promising and effective approach to deliver high antibiotic concentrations at the infection site. OBJECTIVE The objective of this review was to provide a literature review regarding approach to osteomyelitis treatment with antibiotic loaded PMMA. STUDY DESIGN Literature study regarding osteomyelitis treatment with antibiotic loaded carriers using key terms Antibiotic, osteomyelitis, biodegradable PMMA through published articles. Hands searching of bibliographies of identified articles were also undertaken. CONCLUSION We concluded that Antibiotic-impregnated PMMA beads are useful options for the treatment of osteomyelitis for prolonged drug therapy.
Journal Title: Microbial pathogenesis
Year Published: 2017
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