required for the accomplishment of mitosis duration the first a few cell divisions. The cleavage furrow distribution of the protein co-localized with myosin and actin on contractile ring exposes its… Click to show full abstract
required for the accomplishment of mitosis duration the first a few cell divisions. The cleavage furrow distribution of the protein co-localized with myosin and actin on contractile ring exposes its critical and nonsubstitutable role in cytokinesis. Lack of the ECM HF1 leads to defect of the mitosis with generating multinucleate cells. Our data indicate that the function of ECM HF could be a general requirement for cleavage furrow and affected oocyte maturation and fertilization while mouse embryo initiation. This investigations mainly supported by the National Natural Science Foundation of China (31571273and 31371256), the Ministry of Science and Technology of China(2015CB943100), National Department of Education Central Universities Research Fund (GK20130100) and Foreign Distinguished Scientist Program (MS2014SXSF038), Maryland Stem Cell Fund (TEDCO, 2009-MSCRFE-0083-00) and American Heart Association USA (0120673Z).
               
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