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Evolving Models of Heterochromatin: From Foci to Liquid Droplets.

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Two recent papers (Larson et al., 2017; Strom et al., 2017) in Nature propose that heterochromatic domains are organized into phase-separated liquid compartments. Here we highlight the main findings that support the… Click to show full abstract

Two recent papers (Larson et al., 2017; Strom et al., 2017) in Nature propose that heterochromatic domains are organized into phase-separated liquid compartments. Here we highlight the main findings that support the liquid-like nature of HP1 domains and discuss their functional implications in gene silencing and genome organization.

Keywords: evolving models; foci liquid; liquid droplets; models heterochromatin; heterochromatin foci

Journal Title: Molecular cell
Year Published: 2017

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