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Forms and Phases in Huntingtin Protein Aggregation.

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Using a combination of fluorescence microscopy and electron tomography, Peskett et al. (2018), in this issue of Molecular Cell, explore the nucleation of amyloid-like filaments from liquid-like condensates of huntingtin protein… Click to show full abstract

Using a combination of fluorescence microscopy and electron tomography, Peskett et al. (2018), in this issue of Molecular Cell, explore the nucleation of amyloid-like filaments from liquid-like condensates of huntingtin protein exon1 with disease-related polyQ extensions.

Keywords: phases huntingtin; microscopy; huntingtin protein; forms phases; protein aggregation

Journal Title: Molecular cell
Year Published: 2018

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