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Stabbed while Sleeping: Synthetic Retinoid Antibiotics Kill Bacterial Persister Cells.

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Antibiotic-tolerant persister cells are difficult to eradicate by conventional classes of antibiotics. Kim and colleagues have discovered a new class of synthetic retinoid antibiotics that kill Staphylococcus aureus persisters by… Click to show full abstract

Antibiotic-tolerant persister cells are difficult to eradicate by conventional classes of antibiotics. Kim and colleagues have discovered a new class of synthetic retinoid antibiotics that kill Staphylococcus aureus persisters by disrupting their cytoplasmic membrane.

Keywords: synthetic retinoid; retinoid antibiotics; persister cells; antibiotics kill

Journal Title: Molecular cell
Year Published: 2018

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