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Noncoding RNAs (ncRNAs) transcribed from active enhancers are known as enhancer RNAs (eRNAs). eRNAs have generally been shown to contribute to transcriptional activation of target genes in cis. In this… Click to show full abstract
Noncoding RNAs (ncRNAs) transcribed from active enhancers are known as enhancer RNAs (eRNAs). eRNAs have generally been shown to contribute to transcriptional activation of target genes in cis. In this issue, Tsai et al. (2018) demonstrate that an eRNA expressed from a distal enhancer of Myogenic differentiation1 (MyoD) (DRReRNA) does not regulate its neighboring MyoD; instead, it promotes myogenic differentiation by activating Myogenin, which is located on a different chromosome.
Keywords:
myogenin trans;
derived rna;
rna muscles;
muscles regulate;
regulate myogenin;
enhancer derived
Journal Title: Molecular cell
Year Published: 2018
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Journal Title: Molecular cell
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!