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Cryo-EM structures of Dot1L in complex with a ubiquitinated nucleosome provide the long-sought-after molecular mechanism of Dot1L-mediated methylation of lysine 79 in histone H3 and explain crosstalk with histone H2B… Click to show full abstract
Cryo-EM structures of Dot1L in complex with a ubiquitinated nucleosome provide the long-sought-after molecular mechanism of Dot1L-mediated methylation of lysine 79 in histone H3 and explain crosstalk with histone H2B ubiquitination.
Keywords:
histone h3k79;
ubiquitinated nucleosome;
methylation histone;
histone;
dot1l
Journal Title: Molecular cell
Year Published: 2019
Link to full text (if available)
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Journal Title: Molecular cell
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!