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NLRP1: a jack of all trades, or a master of one?

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Recent studies provide evidence that two chemically and mechanistically distinct signals activate the human NLRP1 inflammasome, challenging the concept that it-like other mammalian inflammasomes characterized thus far-evolved to detect and… Click to show full abstract

Recent studies provide evidence that two chemically and mechanistically distinct signals activate the human NLRP1 inflammasome, challenging the concept that it-like other mammalian inflammasomes characterized thus far-evolved to detect and respond to a single danger-associated molecular pattern.

Keywords: nlrp1 jack; trades master; master one; jack trades

Journal Title: Molecular cell
Year Published: 2021

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