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New Type III CRISPR variant and programmable RNA targeting tool: Oh, thank heaven for Cas7-11.

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Özcan et al. (2021) and van Beljouw et al. (2021) characterize a novel Type III-E CRISPR-Cas subtype, composed of a single polypeptide with crRNA processing and sequence-specific RNA cleavage activities, that provides… Click to show full abstract

Özcan et al. (2021) and van Beljouw et al. (2021) characterize a novel Type III-E CRISPR-Cas subtype, composed of a single polypeptide with crRNA processing and sequence-specific RNA cleavage activities, that provides a new RNA knockdown tool for mammalian cells with fewer off-target effects than current technologies.

Keywords: iii crispr; type iii; new type

Journal Title: Molecular cell
Year Published: 2021

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