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Multifunctional supramolecular ionic metallosurfactants (SMIMSs) for antimicrobial, anticancer and serum albumins binding

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Abstract Towards the development of metallodrugs such as metallosurfactants, it is very significant to know about their hydrophobicity, micellization and biological activities. Here, the in vitro biological studies of supramolecular… Click to show full abstract

Abstract Towards the development of metallodrugs such as metallosurfactants, it is very significant to know about their hydrophobicity, micellization and biological activities. Here, the in vitro biological studies of supramolecular ionic metallosurfactants (SMIMSs) namely MOTA, MDTA, MDDTA, MTDTA and MHDTA are chosen to study their effect of hydrophobicity on antimicrobial, anticancer and serum albumins binding activities with UV/Vis and fluorescence spectrophotometer. For antimicrobial studies the Gram positive and negative microbial strains were used and expressed an effective microbial activity against chosen bacteria. Their anticancer activity as compared to control drug are found very effective (GI50

Keywords: antimicrobial anticancer; ionic metallosurfactants; anticancer serum; metallosurfactants smimss; supramolecular ionic; serum albumins

Journal Title: Journal of Molecular Liquids
Year Published: 2018

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