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Abstract Solubility of l -hydroxyproline in water and binary solvent mixtures with methanol, ethanol or n-propanol was systematically determined in a temperature range of 293.15 K–318.15 K under 0.1 MPa. The solubility increased… Click to show full abstract
Abstract Solubility of l -hydroxyproline in water and binary solvent mixtures with methanol, ethanol or n-propanol was systematically determined in a temperature range of 293.15 K–318.15 K under 0.1 MPa. The solubility increased with temperature and increased with increasing composition of water in the binary solvent mixtures. Thermodynamic properties of l -hydroxyproline, such as melting enthalpy, fusion enthalpy and decomposition temperature were determined. Modified Apelblat equation, Jouyban-Acree model, Wilson model, and NRTL model were used to analyze the solubility data and relations with thermodynamic properties of l -hydroxyproline at various solvents.
Journal Title: Journal of Molecular Liquids
Year Published: 2020
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