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Synthesis, characterization and antibacterial effect of diarylmethylamine-based imines

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Abstract Firstly, starting from benzoic acid the diarylmethanone compound was synthesized. The diarylmethanone was converted to the corresponding oxime and then reduced to the diarylmethylamine compound. Four different imine compounds… Click to show full abstract

Abstract Firstly, starting from benzoic acid the diarylmethanone compound was synthesized. The diarylmethanone was converted to the corresponding oxime and then reduced to the diarylmethylamine compound. Four different imine compounds were obtained from the condensation of the diarylmethylamine compound with four different salicylaldehyde derivatives. Antimicrobial activities against Gram (+) and Gram (−) microorganisms (Staphylococcus aureus, Bacillus cereus as the Gram (+); Escherichia coli and Salmonella typhimurium as the Gram (−); and Candida albicans as the fungi) were investigated.

Keywords: characterization antibacterial; synthesis characterization; diarylmethylamine based; effect diarylmethylamine; diarylmethylamine; antibacterial effect

Journal Title: Journal of Molecular Structure
Year Published: 2020

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