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Aqueous Zn2+ analysis: Specific recognition and instant imaging by Schiff base fluorescent probes

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Abstract Two Schiff base fluorescence probes for aqueous Zn2+ were synthesized by introducing salicylaldehyde benzoyl hydrazine as the recognition group and C=N as the characteristic fluorescence chromophore. Spectroscopic analyses, mainly… Click to show full abstract

Abstract Two Schiff base fluorescence probes for aqueous Zn2+ were synthesized by introducing salicylaldehyde benzoyl hydrazine as the recognition group and C=N as the characteristic fluorescence chromophore. Spectroscopic analyses, mainly FS, illuminated the probes’ highly specific recognition towards Zn2+ over other metal ions, accompanied by steady optical properties at a wide pH range of 6.0 to 9.0. Moreover, cytotoxicity and fluorescence imaging in living ECV304 cells identified the probes’ instant response and membrane permeability. These results predicted the probes’ future applications for instant Zn2+ detection in a clinical diagnosis and dynamic analysis of Zn2+ in biological systems.

Keywords: recognition; aqueous zn2; specific recognition; schiff base; zn2

Journal Title: Journal of Molecular Structure
Year Published: 2020

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