LAUSR

Abstract Sarcopenia describes the accelerated loss of skeletal muscle, manifesting as a combination of low muscle strength and low muscle mass. Frailty can be described as the collective deterioration of multiple body systems, leading to reduced ability to maintain homeostasis and respond to physiological stresses placed upon the body. Frailty and sarcopenia are common, especially in hospitalized older people, and also occur at younger ages in the setting of multiple long-term conditions (multimorbidity). There are currently no drug treatments for sarcopenia and frailty, and this is one area of continuing research into these two syndromes. Their diagnosis in clinical practice helps to identify a group of patients at risk of adverse outcomes who could benefit from interventions including resistance exercise training and comprehensive geriatric assessment.