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BACKGROUND Fatigue is prevalent in Multiple Sclerosis (MS), but little research indicates how to best quantify changes in fatigue over time. OBJECTIVE Evaluate reliable change on the abbreviated Modified Fatigue… Click to show full abstract
BACKGROUND Fatigue is prevalent in Multiple Sclerosis (MS), but little research indicates how to best quantify changes in fatigue over time. OBJECTIVE Evaluate reliable change on the abbreviated Modified Fatigue Impact Scale (MFIS-5) in MS patients. METHODS One-hundred sixty eight MS patients completed the MFIS-5 at baseline and follow-up as part of two larger studies. Test-retest reliability scores and reliable change indices were calculated. RESULTS Differences of 4, 5, 6, and 7 points on the MFIS-5 represent statistically meaningful change at the .70, .80, .90, and .95 confidence intervals, respectively. CONCLUSIONS The MFIS-5 can be used to quickly and reliably assess statistically meaningful changes in fatigue among MS patients.
Journal Title: Multiple sclerosis and related disorders
Year Published: 2018
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