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Development of enzyme-based synthetic processes is often hampered by the lack of natural enzymes with requisite properties or specificities. With the potential offered nowadays by computer-aided molecular design and enzyme… Click to show full abstract
Development of enzyme-based synthetic processes is often hampered by the lack of natural enzymes with requisite properties or specificities. With the potential offered nowadays by computer-aided molecular design and enzyme engineering techniques, we have seen in recent years numerous examples of successful enzyme designs that enabled tremendous improvements of catalytic properties for various applications, including catalysis of novel synthetic reactions. Nonetheless, progress in this field, in particular with computational techniques, is still required in order to fasten enzyme design and accelerate the generation of efficient biocatalysts.
Journal Title: New Biotechnology
Year Published: 2018
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